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Stock surge: MoonLake Immunotherapeutics experiences a 41.1% increase in share price on Tuesday

Clinical-stage biotech stock experienced a significant surge in value, increasing almost $3 per share compared to its closing price on Friday.

MoonLake Immunotherapeutics' stock experienced a significant surge, increasing by 41.1%, on...
MoonLake Immunotherapeutics' stock experienced a significant surge, increasing by 41.1%, on Tuesday.

Stock surge: MoonLake Immunotherapeutics experiences a 41.1% increase in share price on Tuesday

MoonLake Immunotherapeutics' Stock Surges on Technical Indicators

MoonLake Immunotherapeutics (MLTX) saw its shares jump 41.1% on Tuesday, marking a continuation of a 25.4% jump on Friday. The surge was primarily due to a technical shift in its stock chart, as the company experienced a KDJ Golden Cross and a bullish Marubozu pattern around 14:00 on August 14, 2025. These technical indicators signal a strong shift in momentum from bearish to bullish and suggest significant buying pressure, which can drive the stock price higher even without recent news or fundamental updates.

At the heart of MoonLake Immunotherapeutics' pipeline is sonelokimab, a nanobody, also known as a single-body antibody, that has shown promise in treating inflammatory diseases. The company recently began a phase 2 trial for sonelokimab to treat patients with moderate to severe hidradenitis, and it has fared well in its phase 2b study as a therapy against psoriasis.

The small size and high solubility and stability of sonelokimab enhance its ability to penetrate tissue, making it a potentially effective treatment for a variety of inflammatory diseases. MoonLake Immunotherapeutics went public in April 2022 via a special purpose acquisition company (SPAC) merger.

However, the company's financials paint a more challenging picture. In the first quarter, MoonLake reported a loss of $2.7 million, and the company's net losses for Q2 2025 amounted to $55.22 million, reflecting elevated expenditures likely tied to clinical development and operational scaling. Despite these losses, analysts remain optimistic overall, with a forecasted strong price upside based on clinical potential and market trends. The stock is seen by some as having a potential upside of about 45%, supported by 16 buy ratings and an average target price near $77.86.

MoonLake's approach with sonelokimab is innovative due to its tri-specific targeting of both IL-17A and IL-17F, aiming to improve efficacy in inflammatory conditions. This sets it apart from existing therapies like Novartis' Cosentyx, a well-established IL-17A inhibitor that currently holds a strong market position in treating psoriasis and related diseases. If successful in clinical trials and regulatory approval, sonelokimab could pose a competitive alternative or complement in this space, addressing some limitations of IL-17A-only inhibitors. However, MoonLake is still in clinical stages without revenue, while Cosentyx is an approved commercial product, so much depends on forthcoming trial outcomes and regulatory milestones.

Investors should closely monitor upcoming clinical trial data, regulatory progress, and the company’s financial health to assess the sustainability of this momentum and the potential for sonelokimab to compete effectively with existing therapies like Cosentyx. As of now, MoonLake Immunotherapeutics has a 52-week high of $15.19 and a low of $4.25, and the stock market value of the company is $336 million. On Tuesday, the stock reached a high of $9 just after the opening bell and closed at $6.38 on Friday, opening at $7.55 on Tuesday. The stock is likely to remain volatile due to its small market cap and newness to the market.

  1. Investors looking to capitalize on potential growth in the medical-conditions sector might consider MoonLake Immunotherapeutics (MLTX) as its stock surged on Tuesday.
  2. Finances, however, paint a more challenging picture, with MoonLake reporting significant losses in Q1 and Q2, reflecting elevated expenditures in clinical development and operational scaling.
  3. Despite the financial challenges, analysts remain optimistic about the stock's potential upside, largely based on the clinical potential and market trends of MoonLake's innovative treatment, sonelokimab.
  4. In the realm of skin-conditions, the money invested in MoonLake could potentially yield returns if sonelokimab, a competing alternative to existing therapies like Novartis' Cosentyx, proves effective in clinical trials and secures regulatory approval.

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