Potential Discovery of a Method for Scar Elimination by Researchers
In a groundbreaking development, a new topical cream named SNT-6302, created by Syntara, has passed Phase 1 human trials. This innovative cream aims to inhibit the production of lysyl oxidase, an enzyme that can cause stiff scar tissue.
The results of the study, which were published in the prestigious journal Science Translational Medicine, suggest that SNT-6302 could be a significant improvement over current scar treatments. These often involve invasive methods such as lasers, injections, or surgery.
The overproduction of lysyl oxidase can cause stiff scar tissue during healing. Lysyl oxidases catalyze collagen cross-linking, a key factor in scar development. By inhibiting this enzyme, SNT-6302 could help improve the appearance and texture of scar tissue.
The scars treated in the study were mature, meaning they no longer showed signs of inflammation. The cream was applied three times per week, and participants treated for 90 days saw a 66 percent reduction in lysyl oxidase activity. Although some participants reported mild to moderate skin irritation, the cream appeared to pass Phase 1 trials, which typically aim to ascertain the safety of new treatments.
Skin scars can have a significant impact on a person's appearance and psychological well-being. In severe cases, the body may produce scar tissue, which is devoid of hair follicles and sweat glands, and typically stiffer and different-looking than healthy skin. This topical cream treatment could offer a less invasive alternative for treating serious scarring.
The study was conducted by Darren Orf, a writer and editor who focuses on science and sci-fi, and his work can be found at Gizmodo and Paste. The manufacturer of SNT-6302 is not yet identified in the available search results.
It's important to note that while these results are promising, further research is needed. The study suggests a future, longer Phase II trial with a larger group of participants. Skin, as the body's first line of defense against pathogens and physical damage, plays a crucial role in our overall health. As research continues, the potential benefits of SNT-6302 could significantly improve the lives of many.
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