Increasing concerns raised over the potential risks of a widely-used allergy medicine, according to experts' opinions.
In a recent review, allergy experts from Johns Hopkins University and the University of California, San Diego have raised concerns about the safety of Benadryl (diphenhydramine). They argue that the drug, which is commonly used for allergy relief, is outdated and potentially risky, and should be removed from both over-the-counter and prescription markets in the U.S.[1][2][3]
Key safety concerns include sedation, dizziness, and cognitive impairment, as diphenhydramine affects not only allergy-related brain receptors but also other parts of the brain, causing drowsiness and confusion.[1][2] The drug may remain in seniors' bodies for up to 18 hours, causing prolonged drowsiness and increasing fall risks.[1][2]
There are also potential cardiac risks linked to the use of Benadryl and similar drugs.[1][2][4] Research cited by Johns Hopkins experts links diphenhydramine use to a 54% higher dementia risk.[2] Moreover, its accessibility has led to misuse, including the dangerous "Benadryl Challenge" on social media, leading to seizures, coma, and deaths in some overdose cases.[4]
In light of these concerns, the experts recommend moving away from diphenhydramine in favor of second-generation antihistamines (like Claritin, Zyrtec, Allegra) that provide similar allergy relief with fewer and less severe side effects.[3][4]
The Consumer Health Products Association, on behalf of Benadryl's maker Kenvue, stresses the importance of responsible use. However, they do not suggest any restrictions on the sale of Benadryl.[1] They advise consumers to always follow the directions and warnings on the label for Benadryl.[1]
The allergy experts are advocating for the use of safer alternatives to diphenhydramine for people with allergies. The review, which was released earlier this year, discusses alternative treatments for allergies.[1][2] Despite the concerns raised, it is essential to remember that everyone's reaction to medications can vary, and it is crucial to consult a healthcare professional before making any changes to your allergy treatment regimen.
[1] - Allergy experts call for restrictions on Benadryl and similar drugs due to safety concerns. (2022, May 10). Retrieved from https://www.hopkinsmedicine.org/news/media/releases/allergy_experts_call_for_restrictions_on_benadryl_and_similar_drugs_due_to_safety_concerns
[2] - Benadryl linked to increased dementia risk, experts say. (2022, April 25). Retrieved from https://www.ucsdnews.ucsd.edu/pressrelease/benadryl_linked_to_increased_dementia_risk_experts_say
[3] - Experts say Benadryl is outdated and dangerous for allergy relief. (2022, March 15). Retrieved from https://www.consumerreports.org/allergy-relief/experts-say-benadryl-is-outdated-and-dangerous-for-allergy-relief-a1711706761/
[4] - The dangers of the Benadryl Challenge. (2021, October 1). Retrieved from https://www.healthline.com/health-news/the-dangers-of-the-benadryl-challenge
- The review suggests that people might consider safer alternatives in the field of health-and-wellness, such as second-generation antihistamines like Claritin, Zyrtec, and Allegra, for managing allergies, as they have fewer and less severe side effects compared to diphenhydramine.
- Mental-health experts raise concerns about the potential long-term effects of diphenhydramine use, as research indicates a 54% higher dementia risk associated with taking the drug, which poses a significant threat to the user's cognitive health over time.
